He has also contributed to the understanding of how sirtuins are modulated by endogenous molecules and pharmacological agents such as resveratrol. In 1999 he was recruited to Harvard Medical School where his laboratory’s research has focused primarily on understanding the role of sirtuins in disease and aging, with associated interests in chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, and cancer. Leonard Guarente where he co discovered a cause of aging for yeast as well as the role of Sir2 in epigenetic changes driven by genome instability. He worked as a postdoctoral researcher at M.I.T. in Molecular Genetics at the University of New South Wales, Sydney in 1995. He is best known for his work on understanding why we age and how to slow its effects. Glenn Center for the Biological Mechanisms of Aging.
is a Professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul F.
